Born in Pennsylvania, Tamara Mancini completed her musical studies at the Mannes School of Music in New York. After winning several vocal competitions, including the Giulio Gari Competition, Licia Albanese Puccini Competition and Opera Index Competition, Mancini joined the San Francisco Opera Adler Fellowship and Merola Opera Center.
Engagements in recent seasons include the title role in Tosca for her debut at the Vancouver Opera, the title role in Turandot at the Royal Opera in Stockholm, Palacio de Bellas Artes in Valencia and with the Pacific Symphony, and her role debut as Chimène in Le Cid with the Odyssey Opera in Boston. In the 2012/13 season, Mancini joined the roster of the Seattle Opera in Das Rheingold and Götterdämmerung and was heard in the role of Ortlinde in Die Walküre. In January of 2012, Mancini appeared at the Teatro Comunale in Bologna as the title role in a new production of Turandot, opposite Yonghoon Lee.
A San Francisco Opera Adler Fellow, Mancini made her debut with the company as Freia in Das Rheingold during the 2008/09 season. In 2010 and 2011, she sang Helmwige in Die Walküre, later appearing with the San Francisco Opera Orchestra at the Stern Grove Music Festival in excerpts from Tosca and La Wally, opposite Marco Berti. Mancini has also prepared and covered such roles for the San Francisco Opera as Marietta in Die Tote Stadt, Elettra in Idomeneo, Giorgetta in Il Tabarro, Desdemona in Otello and the title role in Suor Angelica.
Tamara Mancini has sung under such eminent conductors as Donald Runnicles, Patrick Summers, Giuseppe Finzi, Nicola Luisotti, Michael Tilson Thomas and John DeMain. Other roles in her developing repertoire include Amelia in Un ballo in Maschera, Leonora in La forza del destino, Maddalena di Coigny in Andrea Chenier, and Santuzza in Cavalleria Rusticana.